Association testing of bisulfite-sequencing methylation data via a Laplace approximation

MOTIVATION: Epigenome-wide association studies can provide novel insights into the regulation of genes involved in traits and diseases. The rapid emergence of bisulfite-sequencing technologies enables performing such genome-wide studies at the resolution of single nucleotides. However, analysis of d...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Weissbrod, Omer, Rahmani, Elior, Schweiger, Regev, Rosset, Saharon, Halperin, Eran
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Ismb/Eccb 2017: The 25th Annual Conference Intelligent Systems for Molecular Biology Held Jointly with the 16th Annual European Conference on Computational Biology, Prague, Czech Republic, July 21–25, 2017
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5870555/
https://ncbi.nlm.nih.gov/pubmed/28881982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btx248
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