Association of Methylation Signals With Incident Coronary Heart Disease in an Epigenome-Wide Assessment of Circulating Tumor Necrosis Factor α

IMPORTANCE: Tumor necrosis factor α (TNF-α) is a proinflammatory cytokine with manifold consequences for mammalian pathophysiology, including cardiovascular disease. A deeper understanding of TNF-α biology may enhance treatment precision. OBJECTIVE: To conduct an epigenome-wide analysis of blood-der...

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Detaylı Bibliyografya
Yayımlandı:JAMA Cardiol
Asıl Yazarlar: Aslibekyan, Stella, Agha, Golareh, Colicino, Elena, Do, Anh N., Lahti, Jari, Ligthart, Symen, Marioni, Riccardo E., Marzi, Carola, Mendelson, Michael M., Tanaka, Toshiko, Wielscher, Matthias, Absher, Devin M., Ferrucci, Luigi, Franco, Oscar H., Gieger, Christian, Grallert, Harald, Hernandez, Dena, Huan, Tianxiao, Iurato, Stella, Joehanes, Roby, Just, Allan C., Kunze, Sonja, Lin, Honghuang, Liu, Chunyu, Meigs, James B., van Meurs, Joyce B. J., Moore, Ann Zenobia, Peters, Annette, Prokisch, Holger, Räikkönen, Katri, Rathmann, Wolfgang, Roden, Michael, Schramm, Katharina, Schwartz, Joel D., Starr, John M., Uitterlinden, André G., Vokonas, Pantel, Waldenberger, Melanie, Yao, Chen, Zhi, Degui, Baccarelli, Andrea A., Bandinelli, Stefania, Deary, Ian J., Dehghan, Abbas, Eriksson, Johan, Herder, Christian, Jarvelin, Marjo-Riitta, Levy, Daniel, Arnett, Donna K.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Medical Association 2018
Konular:
Original Investigation
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6100733/
https://ncbi.nlm.nih.gov/pubmed/29617535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamacardio.2018.0510
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