Epigenome-wide association study of whole blood gene expression in Framingham Heart Study participants provides molecular insight into the potential role of CHRNA5 in cigarette smoking-related lung diseases

BACKGROUND: DNA methylation is a key epigenetic modification that can directly affect gene regulation. DNA methylation is highly influenced by environmental factors such as cigarette smoking, which is causally related to chronic obstructive pulmonary disease (COPD) and lung cancer. To date, there ha...

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Detalhes bibliográficos
Publicado no:Clin Epigenetics
Main Authors: Yao, Chen, Joehanes, Roby, Wilson, Rory, Tanaka, Toshiko, Ferrucci, Luigi, Kretschmer, Anja, Prokisch, Holger, Schramm, Katharina, Gieger, Christian, Peters, Annette, Waldenberger, Melanie, Marzi, Carola, Herder, Christian, Levy, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7986283/
https://ncbi.nlm.nih.gov/pubmed/33752734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-021-01041-5
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