Temperature dependent 2(nd) derivative absorbance spectroscopy of aromatic amino acids as a probe of protein dynamics

מאת Esfandiary, Reza, Hunjan, Jagtar S, Lushington, Gerald H, Joshi, Sangeeta B, Middaugh, C Russell
יצא לאור 2009

Improved data visualization techniques for analyzing macromolecule structural changes

מאת Kim, Jae Hyun, Iyer, Vidyashankara, Joshi, Sangeeta B, Volkin, David B, Middaugh, C Russell
יצא לאור 2012

Multidimensional Methods for the Formulation of Biopharmaceuticals and Vaccines

מאת Maddux, Nathaniel R., Joshi, Sangeeta B., Volkin, David B., Ralston, John P., Middaugh, C. Russell
יצא לאור 2011

Crystallization of a nonreplicating rotavirus vaccine candidate

מאת Hong, Moo Sun, Kaur, Kawaljit, Sawant, Nishant, Joshi, Sangeeta B., Volkin, David B., Braatz, Richard D.
הוצא לאור ב Biotechnol Bioeng (2021)

Structural Characterization of IgG1 mAb Aggregates and Particles Generated under Various Stress Conditions

מאת Telikepalli, Srivalli N., Kumru, Ozan S., Kalonia, Cavan, Esfandiary, Reza, Joshi, Sangeeta B., Middaugh, C. Russell, Volkin, David B.
יצא לאור 2014

Formulation and Immunogenicity studies of Type III Secretion System needle antigens as Vaccine Candidates

מאת Barrett, Brooke S., Markham, Aaron P., Esfandiary, Reza, Picking, Wendy L., Picking, William D., Joshi, Sangeeta B., Middaugh, C. Russell
יצא לאור 2010

Understanding the relevance of local conformational stability and dynamics to the aggregation propensity of an IgG1 and IgG2 monoclonal antibodies

מאת Thakkar, Santosh V, Sahni, Neha, Joshi, Sangeeta B, Kerwin, Bruce A, He, Feng, Volkin, David B, Middaugh, C Russell
יצא לאור 2013

Development of Stabilizing Formulations of a Trivalent Inactivated Poliovirus Vaccine in a Dried State for Delivery in the Nanopatch™ Microprojection Array

מאת Wan, Ying, Hickey, John M., Bird, Christopher, Witham, Katey, Fahey, Paul, Forster, Angus, Joshi, Sangeeta B., Volkin, David B.
הוצא לאור ב J Pharm Sci (2018)

Parathyroid hormone is a heparin/polyanion binding protein: Binding energetics and structure modification

מאת Kamerzell, Tim J., Joshi, Sangeeta B., McClean, Donald, Peplinskie, Lori, Toney, Karen, Papac, Damon, Li, Meili, Middaugh, C. Russell
יצא לאור 2007

Biophysical and Stabilization Studies of the Chlamydia trachomatis Mouse Pneumonitis Major Outer Membrane Protein

מאת Cai, Sumin, He, Feng, Samra, Hardeep S., de la Maza, Luis M., Bottazzi, Maria E., Joshi, Sangeeta B., Middaugh, C. Russell
יצא לאור 2009

Comparison of the Structural Stability and Dynamic Properties of Recombinant Anthrax Protective Antigen and its 2-Fluorohistidine Labeled Analogue

מאת Hu, Lei, Joshi, Sangeeta B., Andra, Kiran K., Thakkar, Santosh V., Volkin, David B., Bann, James G., Middaugh, C. Russell
יצא לאור 2012

Development of a candidate stabilizing formulation for bulk storage of a double mutant heat labile toxin (dmLT) protein based adjuvant

מאת Toprani, Vishal M., Sahni, Neha, Hickey, John M., Robertson, George A., Middaugh, C. Russell, Joshi, Sangeeta B., Volkin, David B.
הוצא לאור ב Vaccine (2017)

Effect of Two Emulsion-Based Adjuvants on the Structure and Thermal Stability of S. aureus Alpha-toxin

מאת Wei, Yangjie, Xiong, Jian, Larson, Nicholas R., Iyer, Vidyashankara, Sanyal, Gautam, Joshi, Sangeeta B., Volkin, David B., Middaugh, C. Russell
הוצא לאור ב J Pharm Sci (2018)

Characterizing and Minimizing Aggregation and Particle Formation of Three Recombinant Fusion-Protein Bulk Antigens for Use in a Candidate Trivalent Rotavirus Vaccine

מאת Agarwal, Sanjeev, Sahni, Neha, Hickey, John M., Robertson, George A., Sitrin, Robert, Cryz, Stanley, Joshi, Sangeeta B., Volkin, David B.
הוצא לאור ב J Pharm Sci (2020)

A C-terminal Pfs48/45 malaria transmission-blocking vaccine candidate produced in the baculovirus expression system

מאת Lee, Shwu-Maan, Hickey, John M., Miura, Kazutoyo, Joshi, Sangeeta B., Volkin, David B., King, C. Richter, Plieskatt, Jordan L.
הוצא לאור ב Sci Rep (2020)

An empirical phase diagram approach to investigate conformational stability of “second-generation” functional mutants of acidic fibroblast growth factor-1

מאת Alsenaidy, Mohammad A, Wang, Tingting, Kim, Jae Hyun, Joshi, Sangeeta B, Lee, Jihun, Blaber, Michael, Volkin, David B, Middaugh, C Russell
יצא לאור 2012

Physical stability comparisons of IgG1-Fc variants: effects of N-glycosylation site occupancy and Asp/Gln residues at site Asn 297

מאת ALSENAIDY, MOHAMMAD A., OKBAZGHI, SOLOMON Z., KIM, JAE HYUN, JOSHI, SANGEETA B., MIDDAUGH, C. RUSSELL, TOLBERT, THOMAS J., VOLKIN, DAVID B.
הוצא לאור ב J Pharm Sci (2014)

Effect of acrylodan conjugation and forced oxidation on the structural integrity, conformational stability, and binding activity of a glucose binding protein SM4 used in a prototyp...

מאת Hickey, John M., Sahni, Neha, Chaudhuri, Rajoshi, D'Souza, Ajit, Metters, Andrew, Joshi, Sangeeta B., Russell Middaugh, C., Volkin, David B.
הוצא לאור ב Protein Sci (2017)

Short-term and longer-term protective immune responses generated by subunit vaccination with smallpox A33, B5, L1 or A27 proteins adjuvanted with aluminum hydroxide and CpG in mice...

מאת Xiao, Yuhong, Zeng, Yuhong, Schante, Carole, Joshi, Sangeeta B., Buchman, George W., Volkin, David B., Middaugh, C. Russell, Isaacs, Stuart N.
הוצא לאור ב Vaccine (2020)

Probing protein structure and dynamics by second-derivative ultraviolet absorption analysis of cation–π interactions

מאת Lucas, Laura H., Ersoy, Baran A., Kueltzo, Lisa A., Joshi, Sangeeta B., Brandau, Duane T., Thyagarajapuram, Nagarajan, Peek, Laura J., Middaugh, C. Russell
יצא לאור 2006