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Comparison of the Structural Stability and Dynamic Properties of Recombinant Anthrax Protective Antigen and its 2-Fluorohistidine Labeled Analogue

Protective antigen (PA) is the primary protein antigenic component of both the currently used anthrax vaccine and related recombinant vaccines under development. An analogue of recombinant PA (2-FHis rPA) has been recently shown to block the key steps of pore formation in the process of inducing cyt...

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Dettagli Bibliografici
Autori principali: Hu, Lei, Joshi, Sangeeta B., Andra, Kiran K., Thakkar, Santosh V., Volkin, David B., Bann, James G., Middaugh, C. Russell
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798070/
https://ncbi.nlm.nih.gov/pubmed/22911632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.23294
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