Comparison of the Structural Stability and Dynamic Properties of Recombinant Anthrax Protective Antigen and its 2-Fluorohistidine Labeled Analogue

Protective antigen (PA) is the primary protein antigenic component of both the currently used anthrax vaccine and related recombinant vaccines under development. An analogue of recombinant PA (2-FHis rPA) has been recently shown to block the key steps of pore formation in the process of inducing cyt...

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Autores principales: Hu, Lei, Joshi, Sangeeta B., Andra, Kiran K., Thakkar, Santosh V., Volkin, David B., Bann, James G., Middaugh, C. Russell
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798070/
https://ncbi.nlm.nih.gov/pubmed/22911632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.23294
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