Biophysical characterization and immunization studies of dominant negative inhibitor (DNI), a candidate anthrax toxin subunit vaccine

Dominant negative inhibitor (DNI) is a translocation-deficient homolog of recombinant protective antigen of Bacillus anthracis that is a candidate for a next generation anthrax vaccine. This study demonstrates that the biophysical characteristics of the DNI protein stored in lyophilized form at 4 °C...

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Autors principals: Iyer, Vidyashankara, Hu, Lei, Schanté, Carole E, Vance, David, Chadwick, Chrystal, Jain, Nishant Kumar, Brey, Robert N, Joshi, Sangeeta B, Volkin, David B, Andra, Kiran K, Bann, James G, Mantis, Nicholas J, Middaugh, C. Russell
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2013
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3981845/
https://ncbi.nlm.nih.gov/pubmed/23925275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.25852
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