Glassy-State Stabilization of a Dominant Negative Inhibitor Anthrax Vaccine Containing Aluminum Hydroxide and Glycopyranoside Lipid A Adjuvants

During transport and storage, vaccines may be exposed to temperatures outside of the range recommended for storage, potentially causing efficacy losses. To better understand and prevent such losses, Dominant Negative Inhibitor (DNI), a recombinant protein antigen for a candidate vaccine against anth...

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Veröffentlicht in:J Pharm Sci
Hauptverfasser: Hassett, Kimberly J., Vance, David J., Jain, Nishant K., Sahni, Neha, Rabia, Lilia A., Cousins, Megan C., Joshi, Sangeeta, Volkin, David B., Middaugh, Russell, Mantis, Nicholas J., Carpenter, John F., Randolph, Theodore W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4312196/
https://ncbi.nlm.nih.gov/pubmed/25581103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.24295
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