The antiviral drug ribavirin is a selective inhibitor of S-adenosyl-L-homocysteine hydrolase from Trypanosoma cruzi

Por Cai, Sumin, Li, Qing-Shan, Borchardt, Ronald T., Kuczera, Krzysztof, Schowen, Richard L.
Publicado em 2007

An activation domain within the walleye dermal sarcoma virus retroviral cyclin protein is essential for inhibition of the viral promoter

Por Rovnak, Joel, Hronek, Brett W., Ryan, Sean O., Cai, Sumin, Quackenbush, Sandra L.
Publicado em 2005

Synthesis of 5′-Functionalized Nucleosides: S-Adenosylhomocysteine Analogues with the Carbon-5′ and Sulfur Atoms Replaced by a Vinyl or Halovinyl Unit

Por Wnuk, Stanislaw F., Sacasa, Pablo R., Lewandowska, Elzbieta, Andrei, Daniela, Cai, Sumin, Borchardt, Ronald T.
Publicado em 2008

Comparative kinetics of cofactor association and dissociation for the human and trypanosomal S-adenosylhomocysteine hydrolases. 3. The role of lysyl and tyrosyl residues of the C-t...

Por Cai, Sumin, Fang, Jianwen, Li, Qing-Shan, Borchardt, Ronald T., Kuczera, Krzysztof, Middaugh, C. Russell, Schowen, Richard L.
Publicado em 2010

Evaluation of NAD(H) analogues as selective inhibitors for Trypanosoma cruzi S-Adenosylhomocysteine hydrolase

Por Li, Qing-Shan, Cai, Sumin, Fang, Jianwen, Borchardt, Ronald T., Kuczera, Krzysztof, Middaugh, C. Russell, Schowen, Richard L.
Publicado em 2009

The Rationale for Targeting the NAD/NADH Cofactor Binding Site of Parasitic S-Adenosyl-L-homocysteine Hydrolase for the Design of Anti-parasitic Drugs

Por Cai, Sumin, Li, Qing-Shan, Fang, Jianwen, Borchardt, Ronald T., Kuczera, Krzysztof, Middaugh, C. Russell, Schowen, Richard L.
Publicado em 2009

Biophysical and Stabilization Studies of the Chlamydia trachomatis Mouse Pneumonitis Major Outer Membrane Protein

Por Cai, Sumin, He, Feng, Samra, Hardeep S., de la Maza, Luis M., Bottazzi, Maria E., Joshi, Sangeeta B., Middaugh, C. Russell
Publicado em 2009