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The antiviral drug ribavirin is a selective inhibitor of S-adenosyl-L-homocysteine hydrolase from Trypanosoma cruzi

Ribavirin (1, 2, 4-triazole-3-carboxamide riboside) is a well-known antiviral drug. Ribavirin has also been reported to inhibit human S-adenosyl-L-homocysteine hydrolase (Hs-SAHH), which catalyzes the conversion of S-adenosyl-L-homocysteine to adenosine and homocysteine. We now report that ribavirin...

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Detalhes bibliográficos
Main Authors: Cai, Sumin, Li, Qing-Shan, Borchardt, Ronald T., Kuczera, Krzysztof, Schowen, Richard L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3830956/
https://ncbi.nlm.nih.gov/pubmed/17845853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2007.08.029
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