Integration of pharmaceutical discovery and development : case histories /

Por Borchardt, Ronald T.
Publicado em 1998

Hidalgo, I. J., Raub, T. J., and Borchardt, R. T.: Characterization of the Human Colon Carcinoma Cell Line (Caco-2) as a Model System for Intestinal Epithelial Permeability, Gastro...

Por Borchardt, Ronald T.
Publicado em 2011

Optimizing the "drug-like" properties of leads in drug discovery

Por Borchardt, Ronald T., American Association of Pharmaceutical Scientists.
Publicado em 2006

Comparison of the rates of deamidation, diketopiperazine formation, and oxidation in recombinant human vascular endothelial growth factor and model peptides

Por Goolcharran, Chimanlall, Jones, Andrew J. S., Borchardt, Ronald T.
Publicado em 2000

Effects of inhibitors of spermidine and spermine synthesis on polyamine concentrations and growth of transformed mouse fibroblasts

Por Pegg, Anthony E., Borchardt, Ronald T., Coward, James K.
Publicado em 1981

Effect of N-1 and N-2 residues on peptide deamidation rate in solution and solid state

Por Li, Bei, Schowen, Richard L., Topp, Elizabeth M., Borchardt, Ronald T.
Publicado em 2006

Integration of pharmaceutical discovery and development case histories /

Por Borchardt, Ronald T., Freidinger, Roger M., Sawyer, Tomi K., Smith, Philip L.
Publicado em 1998

The antiviral drug ribavirin is a selective inhibitor of S-adenosyl-L-homocysteine hydrolase from Trypanosoma cruzi

Por Cai, Sumin, Li, Qing-Shan, Borchardt, Ronald T., Kuczera, Krzysztof, Schowen, Richard L.
Publicado em 2007

Prodrugs challenges and rewards part I /

Por Stella, Valentino J., Borchardt, Ronald., Hageman, Michael., Oliyai, Reza., Maag, Hans., Tilley, Jefferson.
Publicado em 2007

Studies of inhibition of rat spermidine synthase and spermine synthase

Por Hibasami, Hiroshige, Borchardt, Ronald T., Chen, Shiang Yuan, Coward, James K., Pegg, Anthony E.
Publicado em 1980

Synthesis of 5′-Functionalized Nucleosides: S-Adenosylhomocysteine Analogues with the Carbon-5′ and Sulfur Atoms Replaced by a Vinyl or Halovinyl Unit

Por Wnuk, Stanislaw F., Sacasa, Pablo R., Lewandowska, Elzbieta, Andrei, Daniela, Cai, Sumin, Borchardt, Ronald T.
Publicado em 2008

Comparative kinetics of cofactor association and dissociation for the human and trypanosomal S-adenosylhomocysteine hydrolases. 3. The role of lysyl and tyrosyl residues of the C-t...

Por Cai, Sumin, Fang, Jianwen, Li, Qing-Shan, Borchardt, Ronald T., Kuczera, Krzysztof, Middaugh, C. Russell, Schowen, Richard L.
Publicado em 2010

Evaluation of NAD(H) analogues as selective inhibitors for Trypanosoma cruzi S-Adenosylhomocysteine hydrolase

Por Li, Qing-Shan, Cai, Sumin, Fang, Jianwen, Borchardt, Ronald T., Kuczera, Krzysztof, Middaugh, C. Russell, Schowen, Richard L.
Publicado em 2009

The Rationale for Targeting the NAD/NADH Cofactor Binding Site of Parasitic S-Adenosyl-L-homocysteine Hydrolase for the Design of Anti-parasitic Drugs

Por Cai, Sumin, Li, Qing-Shan, Fang, Jianwen, Borchardt, Ronald T., Kuczera, Krzysztof, Middaugh, C. Russell, Schowen, Richard L.
Publicado em 2009