Lataa...

Comparative kinetics of cofactor association and dissociation for the human and trypanosomal S-adenosylhomocysteine hydrolases. 3. The role of lysyl and tyrosyl residues of the C-terminal extension

Based on the available X-ray structures of S-adenosylhomocysteine hydrolases (SAHHs), free energy simulations employing the MM-GBSA approach were applied to predict residues important to the differential cofactor binding properties of human and trypanosomal SAHHs (Hs-SAHH and Tc-SAHH), within 5 Å of...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Cai, Sumin, Fang, Jianwen, Li, Qing-Shan, Borchardt, Ronald T., Kuczera, Krzysztof, Middaugh, C. Russell, Schowen, Richard L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2962933/
https://ncbi.nlm.nih.gov/pubmed/20687591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi1007595
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!