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Characterization of human S-adenosyl-homocysteine hydrolase in vitro and identification of its potential inhibitors

Human S-adenosyl-homocysteine hydrolase (SAHH, E.C.3.3.1.1) has been considered to be an attractive target for the design of medicines to treat human disease, because of its important role in regulating biological methylation reactions to catalyse the reversible hydrolysis of S-adenosylhomocysteine...

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Detalhes bibliográficos
Publicado no:J Enzyme Inhib Med Chem
Main Authors: Hao, Weiwei, Li, Yanhua, Shan, Qiuli, Han, Tian, Li, Wencheng, He, Sheng, Zhu, Kongkai, Li, Yumei, Tan, Xiaojun, Gu, Jinsong
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6445193/
https://ncbi.nlm.nih.gov/pubmed/28933241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2017.1370584
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