Characterization of human S-adenosyl-homocysteine hydrolase in vitro and identification of its potential inhibitors

Human S-adenosyl-homocysteine hydrolase (SAHH, E.C.3.3.1.1) has been considered to be an attractive target for the design of medicines to treat human disease, because of its important role in regulating biological methylation reactions to catalyse the reversible hydrolysis of S-adenosylhomocysteine...

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Bibliographische Detailangaben
Veröffentlicht in:J Enzyme Inhib Med Chem
Hauptverfasser: Hao, Weiwei, Li, Yanhua, Shan, Qiuli, Han, Tian, Li, Wencheng, He, Sheng, Zhu, Kongkai, Li, Yumei, Tan, Xiaojun, Gu, Jinsong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2017
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6445193/
https://ncbi.nlm.nih.gov/pubmed/28933241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2017.1370584
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