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Structural insights into the reaction mechanism of S-adenosyl-L-homocysteine hydrolase
S-adenosyl-L-homocysteine hydrolase (SAH hydrolase or SAHH) is a highly conserved enzyme that catalyses the reversible hydrolysis of SAH to L-homocysteine (HCY) and adenosine (ADO). High-resolution crystal structures have been reported for bacterial and plant SAHHs, but not mammalian SAHHs. Here, we...
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| Pubblicato in: | Sci Rep |
|---|---|
| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4647836/ https://ncbi.nlm.nih.gov/pubmed/26573329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16641 |
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