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Structural basis for recognition of 2′,5′-linked oligoadenylates by human ribonuclease L

An interferon-induced endoribonuclease, ribonuclease L (RNase L), is implicated in both the molecular mechanism of action of interferon and the fundamental control of RNA stability in mammalian cells. RNase L is catalytically active only after binding to an unusual activator molecule containing a 5′...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Tanaka, Nobutada, Nakanishi, Masayuki, Kusakabe, Yoshio, Goto, Yoshikuni, Kitade, Yukio, Nakamura, Kazuo T
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2004
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC524351/
https://ncbi.nlm.nih.gov/pubmed/15385955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600420
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