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Structural basis for recognition of 2′,5′-linked oligoadenylates by human ribonuclease L
An interferon-induced endoribonuclease, ribonuclease L (RNase L), is implicated in both the molecular mechanism of action of interferon and the fundamental control of RNA stability in mammalian cells. RNase L is catalytically active only after binding to an unusual activator molecule containing a 5′...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC524351/ https://ncbi.nlm.nih.gov/pubmed/15385955 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600420 |
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