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Crystallization and preliminary X-ray crystallographic study of 1-deoxy-d-xylulose 5-phosphate reductoisomerase from Plasmodium falciparum
The nonmevalonate pathway of isoprenoid biosynthesis present in Plasmodium falciparum is known to be an effective target for antimalarial drugs. The second enzyme of the nonmevalonate pathway, 1-deoxy-d-xylulose 5-phosphate reductoisomerase (DXR), catalyzes the transformation of 1-deoxy-d-xylulose 5...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
International Union of Crystallography
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2833050/ https://ncbi.nlm.nih.gov/pubmed/20208174 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309110001739 |
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