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Crystallization and preliminary X-ray crystallographic study of 1-deoxy-d-xylulose 5-­phosphate reductoisomerase from Plasmodium falciparum

The nonmevalonate pathway of isoprenoid biosynthesis present in Plasmodium falciparum is known to be an effective target for antimalarial drugs. The second enzyme of the nonmevalonate pathway, 1-deoxy-d-xylulose 5-phosphate reductoisomerase (DXR), catalyzes the transformation of 1-deoxy-d-xylulose 5...

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Bibliografiska uppgifter
Huvudupphovsmän: Umeda, Tomonobu, Tanaka, Nobutada, Kusakabe, Yoshio, Nakanishi, Masayuki, Kitade, Yukio, Nakamura, Kazuo T.
Materialtyp: Artigo
Språk:Inglês
Publicerad: International Union of Crystallography 2010
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2833050/
https://ncbi.nlm.nih.gov/pubmed/20208174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309110001739
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