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Structural Characterization of IgG1 mAb Aggregates and Particles Generated under Various Stress Conditions
IgG1 mAb solutions were prepared with and without sodium chloride and subjected to different environmental stresses. Formation of aggregates and particles of varying size was monitored by a combination of size exclusion chromatography (SEC), Nanosight Tracking Analysis (NTA), Micro-flow Imaging (MFI...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4040128/ https://ncbi.nlm.nih.gov/pubmed/24452866 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.23839 |
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