טוען...
Characterization of the Physical Stability of a Lyophilized IgG1 mAb After Accelerated Shipping-like Stress
Upon exposure to shaking stress, an IgG1 mAb formulation in both liquid and lyophilized state formed subvisible particles. Since freeze-drying is expected to minimize protein physical instability under these conditions, the extent and nature of aggregate formation in the lyophilized preparation was...
שמור ב:
| הוצא לאור ב: | J Pharm Sci |
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| Main Authors: | , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2014
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4312241/ https://ncbi.nlm.nih.gov/pubmed/25522000 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.24242 |
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