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Application of radar chart array analysis to visualize effects of formulation variables on IgG1 particle formation as measured by multiple analytical techniques

This study presents a novel method to visualize protein aggregate and particle formation data to rapidly evaluate the effect of solution and stress conditions on the physical stability of an IgG1 monoclonal antibody (mAb). Radar chart arrays were designed so that hundreds of Microflow Digital Imagin...

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Detalles Bibliográficos
Main Authors: Kalonia, Cavan, Kumru, Ozan S., Kim, Jae Hyun, Middaugh, C. Russell, Volkin, David B.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3856888/
https://ncbi.nlm.nih.gov/pubmed/24122556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.23738
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