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Protein Adsorption and Layer Formation at the Stainless Steel–Solution Interface Mediates Shear-Induced Particle Formation for an IgG1 Monoclonal Antibody
Passage of specific protein solutions through certain pumps, tubing, and/or filling nozzles can result in the production of unwanted subvisible protein particles (SVPs). In this work, surface-mediated SVP formation was investigated. Specifically, the effects of different solid interface materials, i...
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| Publicado no: | Mol Pharm |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5997281/ https://ncbi.nlm.nih.gov/pubmed/29425047 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.7b01127 |
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