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Aggregation of a Monoclonal Antibody Induced by Adsorption to Stainless Steel
Stainless steel is a ubiquitous surface in therapeutic protein production equipment and is also present as the needle in some pre-filled syringe biopharmaceutical products. Stainless steel microparticles can cause of aggregation of a monoclonal antibody (mAb). The initial rate of mAb aggregation was...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3926213/ https://ncbi.nlm.nih.gov/pubmed/19725039 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.22525 |
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