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Precipitation of a Monoclonal Antibody by Soluble Tungsten
Tungsten microparticles may be introduced into some pre-filled syringes during the creation of the needle hole. In turn, these microcontaminants may interact with protein therapeutics to produce visible particles. We found that soluble tungsten polyanions formed in acidic buffer below pH 6.0 can pre...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2009
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2749483/ https://ncbi.nlm.nih.gov/pubmed/19230018 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.21707 |
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