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Structural Characterization of IgG1 mAb Aggregates and Particles Generated under Various Stress Conditions
IgG1 mAb solutions were prepared with and without sodium chloride and subjected to different environmental stresses. Formation of aggregates and particles of varying size was monitored by a combination of size exclusion chromatography (SEC), Nanosight Tracking Analysis (NTA), Micro-flow Imaging (MFI...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4040128/ https://ncbi.nlm.nih.gov/pubmed/24452866 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.23839 |
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