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Parathyroid hormone is a heparin/polyanion binding protein: Binding energetics and structure modification

The interaction of four representative polyanions with parathyroid hormone (PTH) residues 1–84 has been investigated utilizing a variety of spectroscopic and calorimetric techniques. Each of the polyanions employed demonstrate enthalpically driven binding to PTH (1–84) with significant affinity. The...

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Detalhes bibliográficos
Main Authors: Kamerzell, Tim J., Joshi, Sangeeta B., McClean, Donald, Peplinskie, Lori, Toney, Karen, Papac, Damon, Li, Meili, Middaugh, C. Russell
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2206658/
https://ncbi.nlm.nih.gov/pubmed/17525467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.062613807
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