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Probing protein structure and dynamics by second-derivative ultraviolet absorption analysis of cation–π interactions

We describe an alternate approach for studying protein structure using the detection of ultraviolet (UV) absorbance peak shifts of aromatic amino acid side chains induced by the presence of salts. The method is based on the hypothesis that salt cations (Li(+), Na(+), and Cs(+)) of varying sizes can...

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Detalhes bibliográficos
Main Authors: Lucas, Laura H., Ersoy, Baran A., Kueltzo, Lisa A., Joshi, Sangeeta B., Brandau, Duane T., Thyagarajapuram, Nagarajan, Peek, Laura J., Middaugh, C. Russell
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2242397/
https://ncbi.nlm.nih.gov/pubmed/16963649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.062133706
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