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Protein-Ligand Interactions: Probing the Energetics of a Putative Cation-π Interaction
In order to probe the energetics associated with a putative cation-π interaction, thermodynamic parameters are determined for complex formation between the Grb2 SH2 domain and tripeptide derivatives of RCO–pTyr–Ac6c–Asn wherein the R group is varied to include different alkyl, cycloalkyl, and aryl g...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4077163/ https://ncbi.nlm.nih.gov/pubmed/24856058 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2014.04.114 |
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