Epigenetics and miRNA emerge as key regulators of smooth muscle cell phenotype and function

per Clifford, Rachel L., Singer, Cherie A., John, Alison E.
Publicat 2012

COVID‐19 and pulmonary fibrosis: A potential role for lung epithelial cells and fibroblasts

per John, Alison E., Joseph, Chitra, Jenkins, Gisli, Tatler, Amanda L.
Publicat a Immunol Rev (2021)

Temporal Production of CCL28 Corresponds to Eosinophil Accumulation and Airway Hyperreactivity in Allergic Airway Inflammation

per John, Alison E., Thomas, Molly S., Berlin, Aaron A., Lukacs, Nicholas W.
Publicat 2005

Abnormal Histone Methylation is Responsible for Increased VEGF165a Secretion from Airway Smooth Muscle Cells in Asthma

per Clifford, Rachel L., John, Alison E., Brightling, Christopher E., Knox, Alan J.
Publicat 2012

Human Airway Smooth Muscle Cells from Asthmatic Individuals Have CXCL8 Hypersecretion Due to Increased NF-κB p65, C/EBPβ, and RNA Polymerase II Binding to the CXCL8 Promoter

per John, Alison E., Zhu, Yong M., Brightling, Christopher E., Pang, Linhua, Knox, Alan J.
Publicat 2009

Fractalkine has anti-apoptotic and proliferative effects on human vascular smooth muscle cells via epidermal growth factor receptor signalling

per White, Gemma E., Tan, Thomas C.C., John, Alison E., Whatling, Carl, McPheat, William L., Greaves, David R.
Publicat 2010

Discovery of a potent nanoparticle P-selectin antagonist with anti-inflammatory effects in allergic airway disease

per John, Alison E., Lukacs, Nicholas W., Berlin, Aaron A., Palecanda, Aiyappa, Bargatze, Robert F., Stoolman, Lloyd M., Nagy, Jon O.
Publicat 2003

CXCL8 histone H3 acetylation is dysfunctional in airway smooth muscle in asthma: regulation by BET

per Clifford, Rachel L., Patel, Jamie K., John, Alison E., Tatler, Amanda L., Mazengarb, Lisa, Brightling, Christopher E., Knox, Alan J.
Publicat a Am J Physiol Lung Cell Mol Physiol (2015)

Secretory leukocyte protease inhibitor gene deletion alters bleomycin-induced lung injury, but not development of pulmonary fibrosis

per Habgood, Anthony N, Tatler, Amanda L, Porte, Joanne, Wahl, Sharon M, Laurent, Geoffrey J, John, Alison E, Johnson, Simon R, Jenkins, Gisli
Publicat a Lab Invest (2016)

Integrin αVβ5 Mediated TGF-β Activation by Airway Smooth Muscle Cells in Asthma

per Tatler, Amanda L, John, Alison E, Jolly, Lisa, Habgood, Anthony, Porte, Jo, Brightling, Chris, Knox, Alan J, Pang, Linhua, Sheppard, Dean, Huang, Xiaozhu, Jenkins, Gisli
Publicat 2011

Amplification of TGFβ Induced ITGB6 Gene Transcription May Promote Pulmonary Fibrosis

per Tatler, Amanda L., Goodwin, Amanda T., Gbolahan, Olumide, Saini, Gauri, Porte, Joanne, John, Alison E., Clifford, Rachel L., Violette, Shelia M., Weinreb, Paul H., Parfrey, Helen, Wolters, Paul J., Gauldie, Jack, Kolb, Martin, Jenkins, Gisli
Publicat a PLoS One (2016)

Reduced Ets Domain-containing Protein Elk1 Promotes Pulmonary Fibrosis via Increased Integrin αvβ6 Expression

per Tatler, Amanda L., Habgood, Anthony, Porte, Joanne, John, Alison E., Stavrou, Anastasios, Hodge, Emily, Kerama-Likoko, Cheryl, Violette, Shelia M., Weinreb, Paul H., Knox, Alan J., Laurent, Geoffrey, Parfrey, Helen, Wolters, Paul John, Wallace, William, Alberti, Siegfried, Nordheim, Alfred, Jenkins, Gisli
Publicat a J Biol Chem (2016)

Translational pharmacology of an inhaled small molecule αvβ6 integrin inhibitor for idiopathic pulmonary fibrosis

per John, Alison E., Graves, Rebecca H., Pun, K. Tao, Vitulli, Giovanni, Forty, Ellen J., Mercer, Paul F., Morrell, Josie L., Barrett, John W., Rogers, Rebecca F., Hafeji, Maryam, Bibby, Lloyd I., Gower, Elaine, Morrison, Valerie S., Man, Yim, Roper, James A., Luckett, Jeni C., Borthwick, Lee A., Barksby, Ben S., Burgoyne, Rachel A., Barnes, Rory, Le, Joelle, Flint, David J., Pyne, Susan, Habgood, Anthony, Organ, Louise A., Joseph, Chitra, Edwards-Pritchard, Rochelle C., Maher, Toby M., Fisher, Andrew J., Gudmann, Natasja Stæhr, Leeming, Diana J., Chambers, Rachel C., Lukey, Pauline T., Marshall, Richard P., Macdonald, Simon J. F., Jenkins, R. Gisli, Slack, Robert J.
Publicat a Nat Commun (2020)

Genetic variants associated with susceptibility to idiopathic pulmonary fibrosis in people of European ancestry: a genome-wide association study

per Allen, Richard J, Porte, Joanne, Braybrooke, Rebecca, Flores, Carlos, Fingerlin, Tasha E, Oldham, Justin M, Guillen-Guio, Beatriz, Ma, Shwu-Fan, Okamoto, Tsukasa, John, Alison E, Obeidat, Ma'en, Yang, Ivana V, Henry, Amanda, Hubbard, Richard B, Navaratnam, Vidya, Saini, Gauri, Thompson, Norma, Booth, Helen L, Hart, Simon P, Hill, Mike R, Hirani, Nik, Maher, Toby M, McAnulty, Robin J, Millar, Ann B, Molyneaux, Philip L, Parfrey, Helen, Rassl, Doris M, Whyte, Moira K B, Fahy, William A, Marshall, Richard P, Oballa, Eunice, Bossé, Yohan, Nickle, David C, Sin, Don D, Timens, Wim, Shrine, Nick, Sayers, Ian, Hall, Ian P, Noth, Imre, Schwartz, David A, Tobin, Martin D, Wain, Louise V, Jenkins, R Gisli
Publicat a Lancet Respir Med (2017)