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Integrin αVβ5 Mediated TGF-β Activation by Airway Smooth Muscle Cells in Asthma
Severe asthma is associated with airway remodelling, characterised by structural changes including increased smooth muscle mass and matrix deposition in the airway, leading to deteriorating lung function. Transforming growth factor-β (TGF-β) is a pleiotropic cytokine leading to increased synthesis o...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3242066/ https://ncbi.nlm.nih.gov/pubmed/22025551 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1003507 |
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