Integrin α(9)β(1) in airway smooth muscle suppresses exaggerated airway narrowing

Exaggerated contraction of airway smooth muscle is the major cause of symptoms in asthma, but the mechanisms that prevent exaggerated contraction are incompletely understood. Here, we showed that integrin α(9)β(1) on airway smooth muscle localizes the polyamine catabolizing enzyme spermidine/spermin...

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Bibliographische Detailangaben
Hauptverfasser: Chen, Chun, Kudo, Makoto, Rutaganira, Florentine, Takano, Hiromi, Lee, Candace, Atakilit, Amha, Robinett, Kathryn S., Uede, Toshimitsu, Wolters, Paul J., Shokat, Kevan M., Huang, Xiaozhu, Sheppard, Dean
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2012
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448403/
https://ncbi.nlm.nih.gov/pubmed/22772469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI60387
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