Integrin α(9)β(1) in airway smooth muscle suppresses exaggerated airway narrowing

Exaggerated contraction of airway smooth muscle is the major cause of symptoms in asthma, but the mechanisms that prevent exaggerated contraction are incompletely understood. Here, we showed that integrin α(9)β(1) on airway smooth muscle localizes the polyamine catabolizing enzyme spermidine/spermin...

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Detalhes bibliográficos
Main Authors: Chen, Chun, Kudo, Makoto, Rutaganira, Florentine, Takano, Hiromi, Lee, Candace, Atakilit, Amha, Robinett, Kathryn S., Uede, Toshimitsu, Wolters, Paul J., Shokat, Kevan M., Huang, Xiaozhu, Sheppard, Dean
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448403/
https://ncbi.nlm.nih.gov/pubmed/22772469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI60387
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