Integrin α(9)β(1) in airway smooth muscle suppresses exaggerated airway narrowing

Exaggerated contraction of airway smooth muscle is the major cause of symptoms in asthma, but the mechanisms that prevent exaggerated contraction are incompletely understood. Here, we showed that integrin α(9)β(1) on airway smooth muscle localizes the polyamine catabolizing enzyme spermidine/spermin...

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Autors principals: Chen, Chun, Kudo, Makoto, Rutaganira, Florentine, Takano, Hiromi, Lee, Candace, Atakilit, Amha, Robinett, Kathryn S., Uede, Toshimitsu, Wolters, Paul J., Shokat, Kevan M., Huang, Xiaozhu, Sheppard, Dean
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448403/
https://ncbi.nlm.nih.gov/pubmed/22772469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI60387
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