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β-Tryptase Regulates IL-8 Expression in Airway Smooth Muscle Cells by a PAR-2–Independent Mechanism

Mast cells are central in the development of several allergic diseases and contain a number of pre-formed mediators. β-tryptase, the most abundant mast cell product, is increasingly recognized as a key inflammatory mediator, as it causes the release of cytokines, particularly the chemokine IL-8, fro...

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Detalhes bibliográficos
Main Authors: Mullan, Charlotte S., Riley, Michael, Clarke, Deborah, Tatler, Amanda, Sutcliffe, Amy, Knox, Alan J., Pang, Linhua
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643247/
https://ncbi.nlm.nih.gov/pubmed/18079491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2007-0082OC
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