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Mast cell tryptase causes airway smooth muscle hyperresponsiveness in dogs.

Supernatants obtained by degranulation of dog mastocytoma cells greatly increased the sensitivity and the magnitude of the contractile response of isolated dog bronchial smooth muscle to histamine. The enhanced contractile response was reversed completely by H1-receptor antagonists and was prevented...

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Detalhes bibliográficos
Main Authors: Sekizawa, K, Caughey, G H, Lazarus, S C, Gold, W M, Nadel, J A
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC303658/
https://ncbi.nlm.nih.gov/pubmed/2642918
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