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Involvement of PTEN in airway hyperresponsiveness and inflammation in bronchial asthma

Phosphatase and tensin homologue deleted on chromosome ten (PTEN) is part of a complex signaling system that affects a variety of important cell functions. PTEN blocks the action of PI3K by dephosphorylating the signaling lipid phosphatidylinositol 3,4,5-triphosphate. We have used a mouse model for...

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Библиографические подробности
Главные авторы: Kwak, Yong-Geun, Song, Chang H., Yi, Ho K., Hwang, Pyoung H., Kim, Jong-Suk, Lee, Kyung S., Lee, Yong C.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2003
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC152583/
https://ncbi.nlm.nih.gov/pubmed/12671058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200316440
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