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Role of cyclo-oxygenase-2 induction in interleukin-1β induced attenuation of cultured human airway smooth muscle cell cyclic AMP generation in response to isoprenaline
1. Airway smooth muscle (ASM) in human asthma shows reduced relaxation and cyclic AMP generation in response to β-adrenoceptor agonists. IL-β attenuates cyclic AMP generation but the underlying mechanism is unclear. We have reported that IL-1β induces cyclo-oxygenase-2 (COX-2) in human ASM cells and...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
1998
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1565701/ https://ncbi.nlm.nih.gov/pubmed/9863663 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702193 |
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