Reducing affinity of αvβ8 interactions with latent TGFβ: dialling down fibrosis

Por Tatler, Amanda L., Jenkins, Gisli
Publicado no Ann Transl Med (2015)

β-Tryptase Regulates IL-8 Expression in Airway Smooth Muscle Cells by a PAR-2–Independent Mechanism

Por Mullan, Charlotte S., Riley, Michael, Clarke, Deborah, Tatler, Amanda, Sutcliffe, Amy, Knox, Alan J., Pang, Linhua
Publicado em 2008

Caffeine inhibits TGFβ activation in epithelial cells, interrupts fibroblast responses to TGFβ, and reduces established fibrosis in ex vivo precision-cut lung slices

Por Tatler, Amanda L, Barnes, Josephine, Habgood, Anthony, Goodwin, Amanda, McAnulty, Robin J, Jenkins, Gisli
Publicado no Thorax (2016)

CXCL8 histone H3 acetylation is dysfunctional in airway smooth muscle in asthma: regulation by BET

Por Clifford, Rachel L., Patel, Jamie K., John, Alison E., Tatler, Amanda L., Mazengarb, Lisa, Brightling, Christopher E., Knox, Alan J.
Publicado no Am J Physiol Lung Cell Mol Physiol (2015)

Transforming Growth Factor-Beta Promotes Rhinovirus Replication in Bronchial Epithelial Cells by Suppressing the Innate Immune Response

Por Bedke, Nicole, Sammut, David, Green, Ben, Kehagia, Valia, Dennison, Patrick, Jenkins, Gisli, Tatler, Amanda, Howarth, Peter H., Holgate, Stephen T., Davies, Donna E.
Publicado em 2012

Secretory leukocyte protease inhibitor gene deletion alters bleomycin-induced lung injury, but not development of pulmonary fibrosis

Por Habgood, Anthony N, Tatler, Amanda L, Porte, Joanne, Wahl, Sharon M, Laurent, Geoffrey J, John, Alison E, Johnson, Simon R, Jenkins, Gisli
Publicado no Lab Invest (2016)

Integrin αVβ5 Mediated TGF-β Activation by Airway Smooth Muscle Cells in Asthma

Por Tatler, Amanda L, John, Alison E, Jolly, Lisa, Habgood, Anthony, Porte, Jo, Brightling, Chris, Knox, Alan J, Pang, Linhua, Sheppard, Dean, Huang, Xiaozhu, Jenkins, Gisli
Publicado em 2011

Investigating lung responses with functional hyperpolarized xenon‐129 MRI in an ex vivo rat model of asthma

Por Lilburn, David M.L., Tatler, Amanda L., Six, Joseph S., Lesbats, Clémentine, Habgood, Anthony, Porte, Joanne, Hughes‐Riley, Theodore, Shaw, Dominick E., Jenkins, Gisli, Meersmann, Thomas
Publicado no Magn Reson Med (2015)

Influenza Promotes Collagen Deposition via αvβ6 Integrin-mediated Transforming Growth Factor β Activation

Por Jolly, Lisa, Stavrou, Anastasios, Vanderstoken, Gilles, Meliopoulos, Victoria A., Habgood, Anthony, Tatler, Amanda L., Porte, Joanne, Knox, Alan, Weinreb, Paul, Violette, Shelia, Hussell, Tracy, Kolb, Martin, Stampfli, Martin R., Schultz-Cherry, Stacey, Jenkins, Gisli
Publicado no J Biol Chem (2014)

Amplification of TGFβ Induced ITGB6 Gene Transcription May Promote Pulmonary Fibrosis

Por Tatler, Amanda L., Goodwin, Amanda T., Gbolahan, Olumide, Saini, Gauri, Porte, Joanne, John, Alison E., Clifford, Rachel L., Violette, Shelia M., Weinreb, Paul H., Parfrey, Helen, Wolters, Paul J., Gauldie, Jack, Kolb, Martin, Jenkins, Gisli
Publicado no PLoS One (2016)

Reduced Ets Domain-containing Protein Elk1 Promotes Pulmonary Fibrosis via Increased Integrin αvβ6 Expression

Por Tatler, Amanda L., Habgood, Anthony, Porte, Joanne, John, Alison E., Stavrou, Anastasios, Hodge, Emily, Kerama-Likoko, Cheryl, Violette, Shelia M., Weinreb, Paul H., Knox, Alan J., Laurent, Geoffrey, Parfrey, Helen, Wolters, Paul John, Wallace, William, Alberti, Siegfried, Nordheim, Alfred, Jenkins, Gisli
Publicado no J Biol Chem (2016)

An Official American Thoracic Society Workshop Report: Use of Animal Models for the Preclinical Assessment of Potential Therapies for Pulmonary Fibrosis

Por Jenkins, R. Gisli, Moore, Bethany B., Chambers, Rachel C., Eickelberg, Oliver, Königshoff, Melanie, Kolb, Martin, Laurent, Geoffrey J., Nanthakumar, Carmel B., Olman, Mitchell A., Pardo, Annie, Selman, Moises, Sheppard, Dean, Sime, Patricia J., Tager, Andrew M., Tatler, Amanda L., Thannickal, Victor J., White, Eric S.
Publicado no Am J Respir Cell Mol Biol (2017)