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Caffeine inhibits TGFβ activation in epithelial cells, interrupts fibroblast responses to TGFβ, and reduces established fibrosis in ex vivo precision-cut lung slices

Caffeine is a commonly used food additive found naturally in many products. In addition to potently stimulating the central nervous system caffeine is able to affect various systems within the body including the cardiovascular and respiratory systems. Importantly, caffeine is used clinically to trea...

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Détails bibliographiques
Publié dans:Thorax
Auteurs principaux: Tatler, Amanda L, Barnes, Josephine, Habgood, Anthony, Goodwin, Amanda, McAnulty, Robin J, Jenkins, Gisli
Format: Artigo
Langue:Inglês
Publié: BMJ Publishing Group 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4893128/
https://ncbi.nlm.nih.gov/pubmed/26911575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thoraxjnl-2015-208215
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