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Discovery of a potent nanoparticle P-selectin antagonist with anti-inflammatory effects in allergic airway disease

The severity of allergic asthma is dependent, in part, on the intensity of peribronchial inflammation. P-selectin is known to play a role in the development of allergen-induced peribronchial inflammation and airway hyperreactivity. Selective inhibitors of P-selectin-mediated leukocyte endothelial-ce...

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Detalhes bibliográficos
Main Authors: John, Alison E., Lukacs, Nicholas W., Berlin, Aaron A., Palecanda, Aiyappa, Bargatze, Robert F., Stoolman, Lloyd M., Nagy, Jon O.
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2839900/
https://ncbi.nlm.nih.gov/pubmed/14563683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.03-0166fje
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