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Notch ligand Delta-like 4 regulates development and pathogenesis of allergic airway responses by modulating IL-2 production and Th2 immunity

Activation of the canonical Notch pathways has been implicated in Th cell differentiation, but the role of specific Notch ligands in Th2 mediated allergic airway responses has not been completely elucidated. In this study, we show that delta-like 4 (Dll4) was up-regulated on dendritic cells in respo...

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Detalhes bibliográficos
Main Authors: Jang, Sihyug, Schaller, Matthew, Berlin, Aaron A., Lukacs, Nicholas W
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2980697/
https://ncbi.nlm.nih.gov/pubmed/20944009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000175
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