Reflections on Darwinian Evolution – Is there a Jewish Perspective?

Por Jacob, Chaim O.
Publicado em 2011

Reply to Sawalha: Evidence for IRAK1 is not evidence against MECP2

Por Jacob, Chaim O., Zidovetzki, Raphael, Mohan, Chandra
Publicado em 2009

Function2Gene: A gene selection tool to increase the power of genetic association studies by utilizing public databases and expert knowledge

Por Armstrong, Don L, Jacob, Chaim O, Zidovetzki, Raphael
Publicado em 2008

Systemic Lupus Erythematosus-associated Neutrophil Cytosolic Factor 2 Mutation Affects the Structure of NADPH Oxidase Complex

Por Armstrong, Don L., Eisenstein, Miriam, Zidovetzki, Raphael, Jacob, Chaim O.
Publicado no J Biol Chem (2015)

Admixture in Hispanic-Americans: Its impact on ITGAM association and implications for admixture mapping in SLE

Por Molineros, Julio E., Kim-Howard, Xana, Deshmukh, Harshal, Jacob, Chaim O., Harley, John B., Nath, Swapan K.
Publicado em 2009

Differential Contribution of IL-4 and STAT6 vs STAT4 to the Development of Lupus Nephritis

Por Singh, Ram Raj, Saxena, Vijay, Zang, Song, Li, Lily, Finkelman, Fred D., Witte, David P., Jacob, Chaim O.
Publicado em 2003

B cell- and BAFF-dependence of IFNα-exaggerated disease in SLE-prone NZM 2328 mice

Por Jacob, Noam, Guo, Shunhua, Mathian, Alexis, Koss, Michael N., Gindea, Simona, Putterman, Chaim, Jacob, Chaim O., Stohl, William
Publicado em 2011

Dispensability of APRIL to development of systemic lupus erythematosus in NZM 2328 mice

Por Jacob, Chaim O., Guo, Shunhua, Jacob, Noam, Pawar, Rahul D., Putterman, Chaim, Quinn, William J., Cancro, Michael P., Migone, Thi-Sau, Stohl, William
Publicado em 2012

Paucity of Clinical Disease despite Serological Autoimmunity and Kidney Pathology in Lupus-Prone New Zealand Mixed 2328 Mice Deficient in BAFF

Por Jacob, Chaim O., Pricop, Luminita, Putterman, Chaim, Koss, Michael N., Liu, Yi, Kollaros, Maria, Bixler, Sarah A., Ambrose, Christine M., Scott, Martin L., Stohl, William
Publicado em 2006

Deficiency of type I IFN receptor in lupus-prone NZM 2328 mice decreases dendritic cell numbers and activation and protects from disease

Por Agrawal, Hemant, Jacob, Noam, Carreras, Esther, Bajana, Sandra, Putterman, Chaim, Turner, Sean, Neas, Barbara, Mathian, Alexis, Koss, Michael N., Stohl, William, Kovats, Susan, Jacob, Chaim O.
Publicado em 2009

Development of systemic lupus erythematosus in NZM 2328 mice in the absence of any single BAFF receptor

Por Jacob, Chaim O., Yu, Ning, Guo, Shunhua, Jacob, Noam, Quinn, William J., Sindhava, Vishal, Cancro, Michael P., Goilav, Beatrice, Putterman, Chaim, Migone, Thi-Sau, Stohl, William
Publicado em 2013

Accelerated Pathological and Clinical Nephritis in Systemic Lupus Erythematosus-Prone New Zealand Mixed 2328 Mice Doubly Deficient in TNF Receptor 1 and TNF Receptor 2 via a Th17-A...

Por Jacob, Noam, Yang, Haitao, Pricop, Luminita, Liu, Yi, Gao, Xiaoni, Zheng, Song Guo, Wang, Juhua, Gao, Hua-Xin, Putterman, Chaim, Koss, Michael N., Stohl, William, Jacob, Chaim O.
Publicado em 2009

IgG1 protects against renal disease in a mouse model of cryoglobulinemia

Por Strait, Richard T., Posgai, Monica T., Mahler, Ashley, Barasa, Nathaniel, Jacob, Chaim O., Köhl, Jörg, Ehlers, Marc, Stringer, Keith, Shanmukappa, Shiva Kumar, Witte, David, Hossain, Md Monir, Khodoun, Marat, Herr, Andrew B., Finkelman, Fred D.
Publicado no Nature (2014)

GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region

Por Armstrong, Don L., Zidovetzki, Raphael, Alarcón-Riquelme, Marta E, Tsao, Betty P, Criswell, Lindsey A, Kimberly, Robert P, Harley, John B, Sivils, Kathy L, Vyse, Timothy J, Gaffney, Patrick M., Langefeld, Carl D, Jacob, Chaim O.
Publicado em 2014

Evaluation of C1q genomic region in minority racial groups of lupus

Por Namjou, Bahram, Gray-McGuire, Courtney, Sestak, Andrea L., Gilkeson, Gary S., Jacob, Chaim O., Merrill, Joan T, James, Judith A, Wakeland, Edward K., Li, Quan-Zhen, Langefeld, Carl D., Divers, Jasmin, Ziegler, Julie, Moser, Kathy L., Kelly, Jennifer A., Kaufman, Kenneth M., Harley, John B.
Publicado em 2009

Subphenotype mapping in systemic lupus erythematosus identifies multiple novel loci associated with circulating interferon alpha

Por Kariuki, Silvia N, Ghodke-Puranik, Yogita, Dorschner, Jessica M, Chrabot, Beverly S, Kelly, Jennifer A, Tsao, Betty P, Kimberly, Robert P, Alarcón-Riquelme, Marta E, Jacob, Chaim O, Criswell, Lindsey A, Sivils, Kathy L, Langefeld, Carl D, Harley, John B, Skol, Andrew D, Niewold, Timothy B
Publicado em 2014

Genetic Analysis of the Pathogenic Molecular Sub-phenotype Interferon Alpha Identifies Multiple Novel Loci Involved in Systemic Lupus Erythematosus

Por Kariuki, Silvia N., Ghodke-Puranik, Yogita, Dorschner, Jessica M., Chrabot, Beverly S., Kelly, Jennifer A., Tsao, Betty P., Kimberly, Robert P., Alarcón-Riquelme, Marta E., Jacob, Chaim O., Criswell, Lindsey A., Sivils, Kathy L., Langefeld, Carl D., Harley, John B., Skol, Andrew D., Niewold, Timothy B.
Publicado no Genes Immun (2014)

Risk Alleles for Systemic Lupus Erythematosus in a Large Case-Control Collection and Associations with Clinical Subphenotypes

Por Taylor, Kimberly E., Chung, Sharon A., Graham, Robert R., Ortmann, Ward A., Lee, Annette T., Langefeld, Carl D., Jacob, Chaim O., Kamboh, M. Ilyas, Alarcón-Riquelme, Marta E., Tsao, Betty P., Moser, Kathy L., Gaffney, Patrick M., Harley, John B., Petri, Michelle, Manzi, Susan, Gregersen, Peter K., Behrens, Timothy W., Criswell, Lindsey A.
Publicado em 2011

Differential Genetic Associations for Systemic Lupus Erythematosus Based on Anti–dsDNA Autoantibody Production

Por Chung, Sharon A., Taylor, Kimberly E., Graham, Robert R., Nititham, Joanne, Lee, Annette T., Ortmann, Ward A., Jacob, Chaim O., Alarcón-Riquelme, Marta E., Tsao, Betty P., Harley, John B., Gaffney, Patrick M., Moser, Kathy L., Petri, Michelle, Demirci, F. Yesim, Kamboh, M. Ilyas, Manzi, Susan, Gregersen, Peter K., Langefeld, Carl D., Behrens, Timothy W., Criswell, Lindsey A.
Publicado em 2011

Lupus-associated causal mutation in neutrophil cytosolic factor 2 (NCF2) brings unique insights to the structure and function of NADPH oxidase

Por Jacob, Chaim O., Eisenstein, Miriam, Dinauer, Mary C., Ming, Wenyu, Liu, Qiang, John, Sutha, Quismorio, Francesco P., Reiff, Andreas, Myones, Barry L., Kaufman, Kenneth M., McCurdy, Deborah, Harley, John B., Silverman, Earl, Kimberly, Robert P., Vyse, Timothy J., Gaffney, Patrick M., Moser, Kathy L., Klein-Gitelman, Marisa, Wagner-Weiner, Linda, Langefeld, Carl D., Armstrong, Don L., Zidovetzki, Raphael
Publicado em 2012