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Development of murine systemic lupus erythematosus in the absence of BAFF
OBJECTIVE: To determine whether SLE can develop in the absence of BAFF in a SLE-prone host. METHODS: Starting with C57BL/6 mice that express a human Bcl2 transgene (Tg) in their B cells (thereby rendering B cell survival largely independent of BAFF-triggered signals), we introgressed this Tg into NZ...
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| Published in: | Arthritis Rheumatol |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6994329/ https://ncbi.nlm.nih.gov/pubmed/31493335 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.41097 |
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