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Development of systemic lupus erythematosus in NZM 2328 mice in the absence of any single BAFF receptor

OBJECTIVE: To determine the necessity for any individual BAFF receptor in the development of SLE. METHODS: Bcma, Taci, and Br3 null mutations were introgressed into NZM 2328 mice. NZM.Bcma(−/−), NZM.Taci(−/−), and NZM.Br3(−/−) mice were evaluated for lymphocyte phenotype and BAFF receptor expression...

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Detalhes bibliográficos
Main Authors: Jacob, Chaim O., Yu, Ning, Guo, Shunhua, Jacob, Noam, Quinn, William J., Sindhava, Vishal, Cancro, Michael P., Goilav, Beatrice, Putterman, Chaim, Migone, Thi-Sau, Stohl, William
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3618582/
https://ncbi.nlm.nih.gov/pubmed/23334904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.37846
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