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Dispensability of APRIL to development of systemic lupus erythematosus in NZM 2328 mice

OBJECTIVE: To determine the role for APRIL in the development of SLE. METHODS: Wild-type (WT) NZM 2328, NZM.April(-/-), NZM.Baff(-/-), and NZM.Baff(-/-).April(-/-) mice were evaluated for lymphocyte phenotype by flow cytometry, for serum total IgG and IgG autoantibody levels by ELISA, for glomerular...

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Detalhes bibliográficos
Main Authors: Jacob, Chaim O., Guo, Shunhua, Jacob, Noam, Pawar, Rahul D., Putterman, Chaim, Quinn, William J., Cancro, Michael P., Migone, Thi-Sau, Stohl, William
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3292707/
https://ncbi.nlm.nih.gov/pubmed/22127792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.33458
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