B cell and/or autoantibody deficiency do not prevent neuropsychiatric disease in murine systemic lupus erythematosus

BACKGROUND: Neuropsychiatric lupus (NPSLE) can be one of the earliest clinical manifestations in human lupus. However, its mechanisms are not fully understood. In lupus, a compromised blood-brain barrier may allow for the passage of circulating autoantibodies into the brain, where they can induce ne...

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書目詳細資料
發表在:J Neuroinflammation
Main Authors: Wen, Jing, Doerner, Jessica, Chalmers, Samantha, Stock, Ariel, Wang, Haowei, Gullinello, Maria, Shlomchik, Mark J., Putterman, Chaim
格式: Artigo
語言:Inglês
出版: BioMed Central 2016
主題:
Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4823887/
https://ncbi.nlm.nih.gov/pubmed/27055816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0537-3
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