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Fn14 deficiency protects lupus-prone mice from histological lupus erythematosus-like skin inflammation induced by ultraviolet light

The cytokine TWEAK and its receptor Fn14 are involved in cell survival and cytokine production. The TWEAK/Fn14 pathway plays a role in the pathogenesis of spontaneous cutaneous lesions in the MRL/lpr lupus strain; however, the role of TWEAK/Fn14 in disease induced by ultraviolet B (UVB) irradiation...

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Detalhes bibliográficos
Publicado no:Exp Dermatol
Main Authors: Doerner, Jessica, Chalmers, Samantha A., Friedman, Adam, Putterman, Chaim
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5127760/
https://ncbi.nlm.nih.gov/pubmed/27305603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/exd.13108
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