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TLR-7-mediated Lupus Nephritis Is Independent of Type I Interferon Signaling
Systemic Lupus Erythematosus (SLE) is an autoimmune disease characterized by increased type I interferons (IFNs), autoantibodies, and inflammatory-mediated multi-organ damage. TLR7 activation is an important contributor to SLE pathogenesis, but the mechanisms by which type I IFNs participate in TLR7...
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| Publicado no: | J Immunol |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6039244/ https://ncbi.nlm.nih.gov/pubmed/29884703 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1701588 |
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