Paucity of Clinical Disease despite Serological Autoimmunity and Kidney Pathology in Lupus-Prone New Zealand Mixed 2328 Mice Deficient in BAFF

Constitutive overexpression of B cell-activating factor belonging to the TNF family (BAFF) promotes development of systemic lupus erythematosus (SLE), and treatment of SLE mice with BAFF antagonists ameliorates disease. To determine whether SLE can develop de novo in BAFF-deficient hosts, BAFF-defic...

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Main Authors: Jacob, Chaim O., Pricop, Luminita, Putterman, Chaim, Koss, Michael N., Liu, Yi, Kollaros, Maria, Bixler, Sarah A., Ambrose, Christine M., Scott, Martin L., Stohl, William
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2896675/
https://ncbi.nlm.nih.gov/pubmed/16888029
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