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Paucity of Clinical Disease despite Serological Autoimmunity and Kidney Pathology in Lupus-Prone New Zealand Mixed 2328 Mice Deficient in BAFF

Constitutive overexpression of B cell-activating factor belonging to the TNF family (BAFF) promotes development of systemic lupus erythematosus (SLE), and treatment of SLE mice with BAFF antagonists ameliorates disease. To determine whether SLE can develop de novo in BAFF-deficient hosts, BAFF-defic...

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Bibliografiske detaljer
Main Authors: Jacob, Chaim O., Pricop, Luminita, Putterman, Chaim, Koss, Michael N., Liu, Yi, Kollaros, Maria, Bixler, Sarah A., Ambrose, Christine M., Scott, Martin L., Stohl, William
Format: Artigo
Sprog:Inglês
Udgivet: 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2896675/
https://ncbi.nlm.nih.gov/pubmed/16888029
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