GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region

In a Genome Wide Association Study (GWAS) of individuals of European ancestry afflicted with Systemic Lupus Erythematosus (SLE) the extensive utilization of imputation, stepwise multiple regression, lasso regularization, and increasing study power by utilizing False Discovery Rate (FDR) instead of a...

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Detalles Bibliográficos
Autores principales: Armstrong, Don L., Zidovetzki, Raphael, Alarcón-Riquelme, Marta E, Tsao, Betty P, Criswell, Lindsey A, Kimberly, Robert P, Harley, John B, Sivils, Kathy L, Vyse, Timothy J, Gaffney, Patrick M., Langefeld, Carl D, Jacob, Chaim O.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156543/
https://ncbi.nlm.nih.gov/pubmed/24871463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gene.2014.23
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