Genetic Analyses of Interferon Pathway-Related Genes Reveals Multiple New Loci Associated with Systemic Lupus Erythematosus (SLE)

OBJECTIVE: The overexpression of interferon (IFN)-inducible genes is a prominent feature of SLE, serves as a marker for active and more severe disease, and is also observed in other autoimmune and inflammatory conditions. The genetic variations responsible for sustained activation of IFN responsive...

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Main Authors: Ramos, Paula S., Williams, Adrienne H., Ziegler, Julie T., Comeau, Mary E., Guy, Richard T., Lessard, Christopher J., Li, He, Edberg, Jeffrey C., Zidovetzki, Raphael, Criswell, Lindsey A., Gaffney, Patrick M., Graham, Deborah Cunninghame, Graham, Robert R., Kelly, Jennifer A., Kaufman, Kenneth M., Brown, Elizabeth E., Alarcón, Graciela S., Petri, Michelle A., Reveille, John D., McGwin, Gerald, Vilá, Luis M., Ramsey-Goldman, Rosalind, Jacob, Chaim O., Vyse, Timothy J., Tsao, Betty P., Harley, John B., Kimberly, Robert P., Alarcón-Riquelme, Marta E., Langefeld, Carl D., Moser, Kathy L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3128183/
https://ncbi.nlm.nih.gov/pubmed/21437871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.30356
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